Research Publications

In silico analysis of identified molecules using LC–HR/MS of Cupressus sempervirens L. ethyl acetate fraction against three monkeypox virus targets

A Linani, K Benarous, E Erol, L Bou-Salah, T Serseg, M Yousfi Journal of Biomolecular Structure and Dynamics, 1-16

Monkeypox virus is a viral disease transmitted to humans through contact with infected animals, such as monkeys and rodents, or through direct contact with the bodily fluids or lesions of infected humans. The aim of this study is to evaluate in silico the inhibition effect of eight Cupressus sempervirens L. ethyl acetate fraction identified molecules using LC-MS on three monkeypox targets such as the vaccinia virus thymidylate kinase (VTK), the viral profilin-like protein (VPP), and the viral RNA polymerase (VRP). The study consist of using molecular docking with AutoDock vina based on the lowest energy value in kcal/mol, pharmacokinetics prediction with pre-ADMET v2.0 server, and prediction of biological activity with the PASS server tool. The best complexes were subjected to molecular dynamics simulation (MD) study to confirm their stability using Desmond software. The used molecules were vitamin C, vanillic …

 

https://www.tandfonline.com/doi/abs/10.1080/07391102.2023.2283149

Kadri, C.B., Guerroudj, A., Hamlat, A. et al. Statistical analysis of remote sensing eco-environmental techniques under land use and land cover constraints: a case study of Blida Province, Algeria. Acta Geophys. (2025). https://doi.org/10.1007/s11600-025-01673-8 https://link.springer.com/article/10.1007/s11600-025-01673-8

The Remote Sensing Ecological Index (RSEI) is widely used to assess environmental quality, yet the influence of weighting methods and land cover types on its outputs remains underexplored. Based on

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Hamlat, A., Kadri, C. B., Sekkoum, M., Guidoum, A., & Remada, A. (2022). Multi-criteria decision-making approach for selecting an alternative wastewater treatment plant site in urban areas of Laghouat (North-Central Algeria). Euro-Mediterranean Journal for Environmental Integration, 7(4), 511–530. https://doi.org/10.1007/s41207-022-00333-3

Environmental projects need decision-making that integrates environmental, socio-political, and economic factors. Finding a suitable location for a wastewater treatment plant (WWTP) can be a complex and challenging task for the

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